W Michael Flanagan Selected Research

SNS 314

3/2010	SNS-314, a pan-Aurora kinase inhibitor, shows potent anti-tumor activity and dosing flexibility in vivo.
9/2009	2-Aminobenzimidazoles as potent Aurora kinase inhibitors.
4/2009	The Aurora kinase inhibitor SNS-314 shows broad therapeutic potential with chemotherapeutics and synergy with microtubule-targeted agents in a colon carcinoma model.

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W Michael Flanagan Research Topics

Disease

3	Neoplasms (Cancer) 03/2010 - 04/2009
2	Melanoma (Melanoma, Malignant) 01/2020 - 03/2010
1	Nausea 01/2020
1	Alopecia (Baldness) 01/2020
1	Diarrhea 01/2020
1	Uveal melanoma 01/2020
1	Fatigue 01/2020
1	Peripheral Nervous System Diseases (PNS Diseases) 01/2020
1	Chills 01/2020
1	Fatty Liver 05/2012
1	Hypercholesterolemia 04/2011
1	Cardiovascular Diseases (Cardiovascular Disease) 04/2011
1	Colonic Neoplasms (Colon Cancer) 03/2010
1	Carcinoma (Carcinomatosis) 04/2009
1	Colorectal Neoplasms (Colorectal Cancer) 04/2009

Drug/Important Bio-Agent (IBA)

3	Aurora KinasesIBA 03/2010 - 04/2009
3	SNS 314IBA 03/2010 - 04/2009
2	Pharmaceutical PreparationsIBA 01/2020 - 04/2009
2	LDL CholesterolIBA 05/2012 - 04/2011
1	Endothelin B ReceptorIBA 01/2020
1	Immunoconjugates (Immunoconjugate)IBA 01/2020
1	Small Interfering RNA (siRNA)IBA 05/2012
1	microsomal triglyceride transfer proteinIBA 05/2012
1	Triglycerides (Triacylglycerol)IBA 05/2012
1	Diacylglycerol O-AcyltransferaseIBA 05/2012
1	oxidized low density lipoproteinIBA 04/2011
1	Histones (Histone)IBA 03/2010
1	Caspase 3 (Caspase-3)IBA 03/2010
1	Urea (Carbamide)FDA LinkGeneric 09/2009
1	2-aminobenzimidazoleIBA 09/2009
1	Carboplatin (JM8)FDA LinkGeneric 04/2009
1	Daunorubicin (Cerubidine)FDA LinkGeneric 04/2009
1	Gemcitabine FDA Link 04/2009
1	Irinotecan (Camptosar)FDA LinkGeneric 04/2009
1	Docetaxel (Taxotere)FDA Link 04/2009
1	Proteins (Proteins, Gene)FDA Link 04/2009
1	Fluorouracil (Carac)FDA LinkGeneric 04/2009
1	Vincristine (Oncovin)FDA LinkGeneric 04/2009